The guidelines list seven prescription medicines and one herbal remedy backed by strong evidence, and include many other treatments that might work for some patients. “Migraine is one of the most disabling conditions known to man, but patients need to know that there is hope,” says Stephen Silberstein, a neurologist at Thomas Jefferson University in Philadelphia and lead author of the guidelines from the American Academy of Neurology and the American Headache Society. They were presented at an academy meeting and published in the journal Neurology. Medicines backed by the strongest evidence include anti-seizure drugs (divalproex sodium, sodium valproate and topiramate), blood pressure drugs (metoprolol, propranolol and timolol) and, for menstrual-related migraines, a medicine called frovatriptan, the guidelines say. They also cite strong support for the herbal remedy butterbur and include a longer list of prescription and non-prescription therapies patients can consider.
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